Cialis And Bph

What is Cialis

Its active ingredient is tadalafil. It was originally known for its long-lasting treatment for erectile dysfunction.

What is BPH (benign prostatic hyperplasia)

BPH, commonly known as "benign prostatic hyperplasia," is a noncancerous enlargement of the prostate. It typically occurs in middle-aged and older men. The enlarged prostate compresses the urethra, leading to a series of urinary symptoms.

How does Cialis (tadalafil) treat BPH
The key point is this: Tadalafil doesn't just "incidentally" improve BPH symptoms; it has been officially approved by drug regulatory authorities in many regions around the world for the treatment of moderate to severe BPH.
Its mechanism of action is primarily twofold:

Relaxing the smooth muscles of the prostate and bladder:
The smooth muscles of the prostate, urethra, and bladder neck are abundantly enriched with phosphodiesterase type 5.
As a PDE5 inhibitor, tadalafil increases cGMP levels in these areas, leading to smooth muscle relaxation.
Effect: This relaxes the squeezed urethra, opening the "faucet," thereby relieving dysuria and improving urine flow.

Improving pelvic blood flow and anti-inflammatory effects

Research suggests that BPH may be associated with chronic ischemia (insufficient blood flow) and inflammation of the prostate and bladder.
Tadalafil can improve blood circulation in the pelvic region, alleviating local tissue hypoxia and inflammation, thereby fundamentally slowing the progression of BPH.

Key Benefits of Using Cialis for BPH Treatment

Kills Two Birds with One Stone, Treating Coexisting Conditions

Many middle-aged and older men with BPH also experience erectile dysfunction.

Tadalafil (especially the low-dose, once-daily regimen) can simultaneously improve urinary symptoms and erectile function, achieving a "double-edged sword" effect. This significantly improves patients' quality of life.

Effectively Improves Lower Urinary Tract Symptoms

Significantly reduces typical symptoms of BPH, including:

Micturition symptoms: straining to urinate, thinning urine stream, prolonged urination, and terminal dribbling.

Storage symptoms: urinary frequency, urgency, and increased nocturia.

Convenient and Long-Lasting Once-Daily Regimen

For the treatment of BPH, the standard dosage is 5 mg once daily.

This regimen maintains stable blood levels, providing 24-hour symptom control, freeing patients from the need to plan when to take their medication and enabling them to lead a more comfortable life.

Dosage and Important Precautions
Dosage:

For patients with isolated BPH or BPH associated with ED, the recommended dose is typically 5 mg once daily.

Important Difference: This differs from the higher doses (10 mg or 20 mg) used on an as-needed basis for ED. This low-dose daily regimen is intended to provide sustained symptom relief.

Time to Onset:

Improvement in urinary symptoms typically requires continued use for several weeks or even months, unlike with rapidly acting alpha-blockers such as tamsulosin. Patients must be patient and persistent in taking the medication.

Side Effects:

Common side effects are related to its vasodilatory effects and include headache, indigestion, back pain, muscle aches, nasal congestion, and flushing. These are generally mild and subside with continued use.

Absolute Contraindications:

Concomitant use with any nitrate medication (such as nitroglycerin or isosorbide mononitrate) is strictly prohibited as it may lead to life-threatening hypotension.

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