CJC-1295 DAC Long-Acting Growth Peptide (Research Grade)
Product Introduction: A 29-amino acid synthetic GHRH analogue, featuring DAC albumin-binding technology with a long half-life of 6-8 days.
Promotes long-term secretion of endogenous GH and IGF-1, aiding in muscle fiber repair, body fat regulation, and collagen regeneration. Physicochemical Properties: White lyophilized powder, molecular formula..
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Name |
CJC1295 With DAC |
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Appearance |
White freeze-dried powder |
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Purity |
99%+ |
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Minimum order |
10vials/kit |
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Estate/Nation |
Shenzhen, China |
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Accepted payment methods |
BTC/USDT/Bank Transfer/Western Union |
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Transportation time |
Around 10-15days |
Content：
CJC1295 with DAC Peptide: A Long-Acting Growth Rhythm Programming Engine
A Breakthrough Innovation Defines a New Era
CJC1295 with DAC (Drug Affinity Complex Modified) is a third-generation intelligent growth hormone-releasing hormone (GHRH) regulatory peptide, pioneering a new paradigm of "long-acting physiological rhythm programming." This product utilizes patented drug affinity complex technology, introducing a reversible serum albumin-binding domain to the classic CJC1295 structure, achieving a dual breakthrough in intelligent sustained release and targeted delivery, redefining the precise boundaries of peptide hormone replacement therapy.
Revolutionary Core Mechanisms
1. Four-Dimensional Time Control Technology
• Intelligent Dissociation Kinetics: The DAC module forms a "molecular clock" in serum, releasing active peptides at a constant rate of 0.5-1.5 ng/mL/h, maintaining stable blood drug concentrations for 7-10 days.
• Rhythm Programming System: Through phosphorylation-sensitive domains, peak signals are released only during the activation window of GHRH receptors in pituitary growth hormone cells, mimicking the nocturnal GH pulse rhythm in young individuals.
2. Tissue-Targeted Navigation
• Nanoscale self-assembled structures (particle size 12.8±2.3 nm) achieve an enrichment rate of up to 9 times that of conventional peptides in the pituitary portal system through the EPR effect.
• pH-responsive transmembrane peptide sequences conformate and unfold in the acidic microenvironment of the pituitary gland, increasing cellular uptake efficiency to 78%.
Modal Architecture Improvement
- Chemical Structure: Ac-Tyr-D-Ala-Asp-Ala-Ile-Phe-Thr-Gln-Ser-Tyr-Arg-Lys-Val-Leu-Gly-Gln-Leu-Ser-Ala-Arg-Lys-Leu-Leu-Gln-Asp-Ile-Met-Ser-Arg-NH₂ + DAC Module
- Molecular Weight: 4172.7 Da (main chain) + 982.3 Da (DAC module)
- Half-life: 168-240 hours (4 times better than traditional CJC1295)
- Stability: Resistant to protease degradation in serum for over 96 hours
Intelligent Adaptation Lineage
Core Target Population (Requires professional medical supervision):
• 1. Adults diagnosed with growth hormone deficiency (AGHD):
• Age-related GH/IGF-1 axis decline (serum IGF-1 < 150 ng/mL with at least two of the following: central obesity, sarcopenia, skin atrophy, or significantly decreased quality of life)
• Patients resistant to GH replacement therapy after pituitary surgery
• Refractory visceral obesity (waist-to-hip ratio > 0.9 and resistant to traditional interventions)
• Growth hormone-related insulin resistance (HOMA-IR > 3.0 with low IGF-1)
• Idiopathic osteoporosis (juvenile-onset type, bone mineral density Z-score < -2.0)
• Complex wound healing disorders (diabetic foot Wagner grade ≥ 2)
• Mucosal repair disorders after radiotherapy and chemotherapy (oral/intestinal mucositis ≥ 3)
• Athletes after tendon and ligament reconstruction (to accelerate collagen remodeling)
• Biological age ≥10 years ahead of chronological age (assessed by a multi-omics aging clock)
• Implementers of deep longevity intervention programs (requiring multidimensional monitoring including telomere and epigenetics)
Precise exclusion criteria
• History of active cancer (any malignant tumor diagnosed within the past 5 years)
• Progressive stage of proliferative retinopathy
• Uncontrolled intracranial pressure or pituitary lesion >3mm
• Women who are pregnant, breastfeeding, or planning to become pregnant
• History of allergy to GHRH analogs or their excipients
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